MSDS for 1,2-Ethanedithiol

Identification

Product Name: 1,2-Ethanedithiol
Chemical Formula: C2H6S2
Synonyms: Ethylene dithiol, Ethane-1,2-dithiol
CAS Number: 540-63-6
Recommended Use: Industrial manufacturing, laboratory reagent
Supplier Identification: Manufacturer or distributor address and contact information
Emergency Phone: Local or company emergency number; poison control

Hazard Identification

GHS Classification: Acute toxicity (oral, dermal, inhalation) – Category 3; Skin corrosion – Category 1B; Eye damage – Category 1; Flammable liquid – Category 3
Signal Word: Danger
Pictograms: Skull and crossbones, Corrosion, Flame
Hazard Statements: Toxic if swallowed, in contact with skin or if inhaled; Causes severe skin burns and eye damage; Flammable liquid and vapor
Precautionary Statements: Avoid all unnecessary exposure, use protective equipment, keep away from ignition sources, store tightly closed in a well-ventilated place
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Target Organs: Eyes, skin, respiratory system

Composition / Information on Ingredients

Chemical Name: 1,2-Ethanedithiol
Concentration: >98% by weight
Impurities/Stabilizers: Trace water, possible low-level organic sulfur contaminants
Molecular Weight: 94.2 g/mol

First Aid Measures

Inhalation: Move affected individual to fresh air, supply oxygen by trained personnel if breathing is difficult, seek immediate medical attention
Skin Contact: Rinse skin with plenty of running water for at least 15 minutes, remove contaminated clothing, get medical help for burns or persistent irritation
Eye Contact: Rinse eyes carefully with water for several minutes, lift eyelids occasionally, obtain medical attention urgently
Ingestion: Do not induce vomiting, rinse mouth with water, seek immediate medical advice and treatment, risk of severe irritation or poisoning
Notes for Physician: Provide treatment for corrosive substances and possible organosulfur toxicity, watch for respiratory issues

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, alcohol-resistant foam, carbon dioxide
Unsuitable Extinguishing Media: Direct water jet
Specific Hazards: Releases toxic gases such as sulfur oxides, hydrogen sulfide, and carbon monoxide in a fire
Protective Equipment: Wear self-contained breathing apparatus and full protective gear
Special Procedures: Cool containers with spray water away from fire zone, evacuate area if necessary, avoid inhaling vapors or gases
Combustion Products: Sulfur dioxide, carbon oxides, hydrogen sulfide

Accidental Release Measures

Personal Precautions: Use appropriate personal protective equipment, avoid skin or eye contact, ventilate area
Environmental Precautions: Prevent discharge into drains, waterways, or soil since contamination may harm aquatic environments
Cleanup Methods: Absorb with inert material such as sand or vermiculite, collect and dispose of using sealed labeled waste containers, wash spill area with water and detergent, ventilate thoroughly
Emergency Procedures: Restrict access, notify authorities if large quantities escape, provide trained personnel for response

Handling and Storage

Handling Precautions: Handle only with proper ventilation, use chemical-resistant gloves and goggles, avoid inhaling vapors, do not eat or drink near handling area
Storage Conditions: Keep container tightly closed, store in cool well-ventilated locations away from heat and sparks
Incompatible Materials: Strong oxidizers, acids, bases, sources of ignition
Transfer Guidance: Ground and bond containers during liquid transfer, use only in chemical fume hood or with suitable local extraction

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established OSHA or ACGIH threshold values; minimize exposure as much as possible
Engineering Controls: Use fume hood, local exhaust ventilation
Personal Protective Equipment: Chemical-resistant gloves (nitrile or rubber), tightly sealed safety goggles or face shield, flame-resistant lab coat, chemical-resistant apron, suitable respiratory protection if vapors are present
Hygiene Measures: Wash thoroughly after handling, remove contaminated clothing, do not eat, drink, or smoke in work area

Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Strong, unpleasant, rotten egg or garlic-like
Odor Threshold: Extremely low, easily detectable
pH: Not applicable (non-aqueous)
Melting Point: -85°C
Boiling Point: 146-148°C
Flash Point: 49°C (closed cup)
Flammability: Flammable
Vapor Pressure: 5 mmHg at 20°C
Vapor Density: 3.2 (air = 1)
Solubility: Slightly soluble in water; soluble in ethanol, diethyl ether, acetone
Specific Gravity: 1.09 (water = 1)
Partition Coefficient: Log Kow: 0.17
Decomposition Temperature: Information not fully available, decomposes with sulfur oxide emission
Evaporation Rate: Not readily available
Auto-ignition Temperature: ~235°C
Explosive Limits: 2.1% - 20.2% (v/v in air)

Stability and Reactivity

Chemical Stability: Stable at standard temperatures and storage conditions
Reactivity: Reacts violently with strong oxidizers, acid chlorides
Hazardous Reactions: Mixing with acids or oxidizers releases toxic gases
Conditions to Avoid: Heat, flames, sparks, sunlight, contact with incompatible chemicals
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, sulfur oxides, hydrogen sulfide

Toxicological Information

Routes of Exposure: Skin absorption, inhalation, ingestion, eye contact
Acute Toxicity: LD50 (oral, rat): 160 mg/kg; LD50 (dermal, rabbit): 380 mg/kg
Short-Term Effects: Severe poisoning, burns to skin and eyes, harmful if inhaled or swallowed, may cause nausea, headache, dizziness, respiratory distress
Long-Term Effects: Chronic exposures may damage liver, kidneys, and central nervous system
Symptoms of Exposure: Burning, tearing, coughing, labored breathing, convulsions at high doses
Sensitization: No known data
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Mutagenicity: No conclusive data; avoid exposure
Reproductive toxicity: No available evidence in published studies

Ecological Information

Ecotoxicity: Toxic to aquatic life, rapid spread through water due to miscibility with organics
Persistence/Degradability: Expected to degrade slowly in environment, may persist in water and soil
Bioaccumulation Potential: Low potential for bioconcentration, but may cause local aquatic toxicity
Mobility in Soil: Likely to be highly mobile
Aquatic Toxicity: LC50 (fish): data limited; estimated harmful at low concentrations
Other Adverse Effects: Bad odor may lead to public nuisance and indirect ecological effects

Disposal Considerations

Waste Treatment Methods: Incinerate in approved facility with afterburner and scrubber for sulfur compounds
Disposal Containers: Use sealed, chemical-resistant containers, clearly labeled as hazardous waste
Special Precautions: Never pour into drains, watercourses, or soil
Contaminated Packaging: Rinse thoroughly, treat as hazardous waste
Applicable Regulations: Follow all federal, state, and local requirements for hazardous waste disposal

Transport Information

UN Number: UN3335
Proper Shipping Name: 1,2-Ethanedithiol
Transport Hazard Class: 3 (Flammable liquids)
Packing Group: II
Labels: Flammable liquid, Toxic
Special Precautions: Avoid rough handling, keep away from food and feed, carry separate from oxidizers or acids
Marine Pollutant: Yes
Regulatory References: Refer to ADR/RID, IMDG, IATA

Regulatory Information

OSHA: Hazardous Chemical, subject to OSHA 1910.1200
EPA: Listed as hazardous substance under RCRA
TSCA: Registered under TSCA inventory
SARA Title III: Listed for acute health risk
WHMIS (Canada): Class B2 (flammable), D1A (very toxic), E (corrosive)
REACH (Europe): Substance registration in place
Other Local/Regional: Observe all country and local requirements for hazardous chemicals