Material Safety Data Sheet for 1-Octadecanethiol

Identification

Product Name: 1-Octadecanethiol
Synonyms: Octadecyl mercaptan, Stearyl mercaptan
Chemical Formula: C18H38S
CAS Number: 2885-00-9
Recommended Use: Academic research, surface modification, specialty chemical synthesis
Manufacturer: Refer to label or supplier contact information
Emergency Contact Number: Provided by distributor or local authority
Product Codes: Varies by supplier

Hazard Identification

Classification: Flammable liquid (Category 4); Acute toxicity, oral (Category 4); Skin irritation (Category 2); Eye irritation (Category 2A)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may cause respiratory irritation
Precautionary Statements: Avoid breathing fumes and vapors, wash skin thoroughly after handling, use only outdoors or in well-ventilated area, wear protective gloves and eye protection
Potential Health Effects: Inhalation may cause irritation, ingestion can cause gastrointestinal pain, skin contact leads to irritation, repeated or prolonged exposure may aggravate preexisting skin or respiratory conditions
Environmental Impacts: Harmful to aquatic life, can cause long-lasting adverse effects in aquatic environments

Composition / Information on Ingredients

Chemical Name: 1-Octadecanethiol
Concentration: ≥98%
Molecular Weight: 286.56 g/mol
Additives or Impurities: Typical samples contain minor impurities from synthesis, details may be available on batch COA
Ingredient Classification: Not a mixture, single-component substance

First Aid Measures

Inhalation: Move person to fresh air, keep comfortable for breathing, seek medical attention if symptoms like coughing or shortness of breath persist
Skin Contact: Immediately wash skin with soap and plenty of water, remove contaminated clothing, seek medical advice for persistent irritation
Eye Contact: Rinse cautiously with water for at least 15 minutes, lift upper and lower eyelids occasionally, get medical assistance if discomfort continues
Ingestion: Rinse mouth, do not induce vomiting, call a poison control center or physician for advice, offer water if conscious

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, CO2, foam, or water spray
Specific Hazards During Fire: Fumes may contain carbon oxide, sulfur oxides, and other toxic vapors if burned
Protective Equipment: Firefighters need a self-contained breathing apparatus and full protective gear to handle chemical fires
Special Procedures: Cool containers with water spray to prevent rupture from heat exposure, use caution as material is slippery when spilled

Accidental Release Measures

Personal Precautions: Avoid contact with skin and eyes, ventilate area, wear chemical-resistant gloves, protective clothing, and eye protection
Spill Clean-up Methods: Absorb with earth, sand, or other inert absorbent material; collect waste in suitable container for disposal
Preventing Environmental Release: Block entry to drains or watercourses, report large releases to environmental authorities
Additional Considerations: Use tools made of materials that will not spark, avoid raising dust or aerosols during cleanup

Handling and Storage

Precautions for Handling: Avoid breathing vapors or dust, keep away from ignition sources, avoid contact with skin and eyes, do not eat or drink while handling
Storage Conditions: Keep tightly closed in a dry, cool, well-ventilated space, protect from direct sunlight and incompatible substances
Incompatibles: Strong oxidizers such as peroxides, nitric acid, may react violently; avoid contact with strong bases
Other Safety Measures: Label all storage containers clearly, inspect for leaks or corrosion regularly

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific regulatory limits set for 1-Octadecanethiol, observe general chemical exposure guidance
Controls: Use fume hoods or local exhaust for large-scale work, supply eyewash stations and safety showers in work area
Personal Protective Equipment: Chemical safety goggles, face shield for splash risk, nitrile or butyl-rubber gloves, lab coat or coveralls
Respiratory Protection: Air-purifying respirator with organic vapor cartridge for concentrations above safe exposure levels
Hygiene Measures: Wash hands thoroughly after handling, change out of contaminated clothing before breaks and end of shift

Physical and Chemical Properties

Appearance: White to off-white solid or waxy crystalline
Odor: Mild, unpleasant, typical of thiols
Melting Point: 36-38°C
Boiling Point: 351°C
Flash Point: 140°C (Closed cup)
Vapor Pressure: Very low at 25°C
Solubility in Water: Insoluble
Solubility in Organic Solvents: Soluble in alcohol, chloroform, ether
Partition Coefficient (log Kow): High (strongly hydrophobic)
Density: 0.85–0.90 g/cm³
Viscosity: Not readily measurable due to waxy solid state
Decomposition Temperature: Typically above 200°C
Evaporation Rate: Negligible
Explosion Limits: Not determined

Stability and Reactivity

Chemical Stability: Stable under recommended conditions, may darken on exposure to air or light
Incompatible Materials: Strong oxidizing agents, acids, some bases
Hazardous Reactions: Not prone to dangerous polymerization; may react with oxidizers to generate heat
Thermal Decomposition Products: Carbon monoxide, carbon dioxide, sulfur oxides, hydrocarbons
Conditions to Avoid: High temperatures, sources of ignition, prolonged exposure to air or sunlight

Toxicological Information

Acute Toxicity (Oral LD50): Data for this compound limited, structurally similar thiols suggest moderate oral toxicity
Acute Toxicity (Inhalation): Irritating effects possible but not acutely toxic at low concentrations
Skin and Eye Irritation: Causes irritation, may lead to redness, itching, or swelling
Chronic Exposure: Prolonged or repeated contact may dry or crack skin, sensitization unlikely
Carcinogenicity: No data indicating carcinogenic risks
Mutagenicity/Reproductive Toxicity: Lacking data for this molecule, standard precautionary measures advised
Symptoms: Inhalation or skin contact can bring respiratory discomfort, nausea, headache, or vomiting in sensitive individuals

Ecological Information

Aquatic Toxicity: Harmful to aquatic life, long-term effects in aquatic environments cannot be ruled out
Persistence and Degradability: Expected to be slowly biodegradable; strong hydrophobicity may hinder breakdown in soil or water
Bioaccumulation Potential: High; log Kow indicates accumulation in aquatic organisms
Mobility in Soil: Limited water mobility; will absorb to soils or sediments
Additional Considerations: Product should not be released to environment without proper treatment; avoid discharge to surface waters or drains

Disposal Considerations

Disposal Methods: Incinerate at a licensed chemical disposal facility; avoid landfill if possible
Container Disposal: Triple rinse with solvent, puncture or break to prevent reuse, dispose via hazardous waste route
Environmental Precautions: Do not discharge to sewers, surface water, or soil
Regulatory Compliance: Confirm waste handling with local, regional, and national waste authorities

Transport Information

UN Number: Not allocated for this substance
Proper Shipping Name: Chemicals, not otherwise specified
Hazard Class: Not classified as hazardous for transport under most regulations
Packing Group: Not applicable
Marine Pollutant: Not listed; caution needed for large-scale spills
Special Transport Precautions: Secure packaging to avoid leaks, label outer containers with identity and hazard warnings, keep away from incompatible substances during shipment

Regulatory Information

TSCA Status: Listed in the United States Toxic Substances Control Act Inventory
REACH Registration: Registered or exempted under European Union REACH regulations
OSHA Hazard Communication: Covered under workplace hazard communication standard
WHMIS Classification (Canada): Classified as hazardous
Other International Regulations: Subject to standard workplace safety, storage, and disposal regulations in many countries
Labeling Requirements: Must show hazard pictograms and warnings as per GHS
Restrictions: None specifically identified for private or research use, but confirm statutory or workplace-specific restrictions before use