MSDS of 3,3'-Dithiodipropionic Acid
1. Identification
Product Name: 3,3'-Dithiodipropionic Acid
Synonyms: β,β'-Dithiodipropionic acid, DTDPA
Chemical Formula: C6H10O4S2
CAS Number: 105-57-7
Manufacturer: Supplier contact details and emergency phone numbers found on the product label or shipping documents
Recommended Use: Laboratory research, intermediate for synthesis, crosslinking agent
Restrictions: Industrial, research, or professional use only; not for household use or food/drug applications
2. Hazard Identification
Classification: Eye irritant (Category 2), Skin irritant (Category 2)
Hazard Statements: Causes skin irritation, causes serious eye irritation, may cause respiratory irritation on dust inhalation
Signal Word: Warning
Pictograms: Exclamation mark (GHS07)
Precautionary Statements: Wash hands thoroughly after handling, wear protective gloves/eye protection, avoid dust generation, do not breathe dust
Other Hazards: Not considered combustible but may decompose under fire conditions to release toxic gases
3. Composition / Information on Ingredients
Chemical Name: 3,3'-Dithiodipropionic Acid
Common Name: DTDPA
CAS Number: 105-57-7
Concentration: Greater than 98%
Impurities or Stabilizing Additives: No hazardous impurities above OSHA or WHMIS thresholds
Molecular Weight: 210.28 g/mol
4. First Aid Measures
Inhalation: Move person to fresh air, keep comfortable, seek medical attention if symptoms develop such as coughing or shortness of breath
Skin Contact: Remove contaminated clothes, wash with plenty of water and soap for at least 15 minutes, seek medical advice if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, hold eyelids apart, remove contact lenses if present and easy, get medical care
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical help
Symptoms: Skin redness, itching, burning feeling, eye discomfort, mild respiratory symptoms
5. Fire-Fighting Measures
Suitable Extinguishing Media: Dry chemical, carbon dioxide, water spray, foam
Unsuitable Extinguishing Media: Direct water jet; may spread powder
Specific Hazards: Can give off irritating or toxic fumes (sulfur oxides, carbon oxides) in fire
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective suit
Advice for Firefighters: Keep containers cooled with water, avoid breathing dust and combustion gases
6. Accidental Release Measures
Personal Precautions: Use appropriate personal protective equipment (gloves, goggles, protective clothing), avoid breathing dust
Environmental Precautions: Prevent entry into waterways, sewers, soil and drains
Cleanup Methods: Sweep up spill with non-sparking tools, use damp cloth to wipe, store collected material in labeled waste container, ventilate area
Decontamination Procedures: Wash spill site after material pickup is complete
Emergency Procedures: Evacuate area if large spill, ensure proper ventilation, report to authorities if necessary
7. Handling and Storage
Handling: Keep powder generation to a minimum, handle with care, avoid skin and eye exposure, wash hands and face after handling
Storage: Store in tightly closed original container, in a cool, dry, well-ventilated area away from incompatible substances
Incompatibilities: Strong oxidizing agents, strong bases, strong reducing agents, moisture
Storage Temperature: Not above 25°C, protect from humidity and heat
Special Requirements: Maintain proper labeling on container, use secondary containment for storage
8. Exposure Controls and Personal Protection
Engineering Controls: Use local exhaust ventilation to keep airborne dust levels low, work in fume hood if dust generated
Exposure Limits: No specific ACGIH, NIOSH, or OSHA limits for 3,3'-dithiodipropionic acid
Personal Protective Equipment: Nitrile or similar protective gloves, safety goggles or full-face shield, laboratory coat, dust mask or respirator for large-scale handling
Hygiene Measures: Wash thoroughly after handling, change contaminated clothes
Environmental Exposure Controls: Prevent spills, use closed containers, avoid aerosol or powder release
9. Physical and Chemical Properties
Appearance: White to off-white crystalline powder
Odor: Odorless or faint characteristic odor
Melting Point: 158–162°C
Boiling Point: Not determined; decomposes
Solubility: Slightly soluble in water, more soluble in organic solvents like ethanol, methanol
Density: Around 1.6 g/cm³
pH: Not available (acidic solution expected)
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): Not available
Other Data: Stable under standard handling and storage conditions
10. Stability and Reactivity
Chemical Stability: Stable in closed containers at room temperature and low humidity
Reactivity: Reacts with strong oxidants, may react with bases or reducing agents
Hazardous Reactions: No dangerous polymerization expected under normal conditions
Conditions to Avoid: Excess heat, moisture exposure, direct sunlight, open flames, strong oxidants
Decomposition Products: Sulfur oxides, carbon dioxide, carbon monoxide
11. Toxicological Information
Acute Toxicity: Data limited, estimated low toxicity by oral, dermal, inhalation routes
Skin Corrosion/Irritation: Causes mild to moderate skin irritation
Eye Damage/Irritation: Causes moderate to severe irritation to eyes
Respiratory Sensitization: Dusts may cause irritation of respiratory system
Skin Sensitization: Not classified based on available information
Repeated Dose Toxicity: Long-term effects not well documented, avoid prolonged exposure
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, OSHA
Mutagenicity: Not listed for mutagenic effects in standard tests
Reproductive Toxicity: No available studies indicate reproductive or developmental harm
Medical Conditions Aggravated: Preexisting skin or eye disorders may be aggravated
12. Ecological Information
Toxicity to Aquatic Life: No specific data, avoid uncontrolled release to waterways
Persistence/Degradability: Not rapidly biodegradable, may degrade slowly in environment
Bioaccumulation Potential: Limited data, potential for low bioaccumulation due to chemical structure
Mobility in Soil: Not highly mobile; limited by low solubility in water
Other Adverse Effects: No evidence for large-scale environmental hazards, use good chemical management practices to minimize risk
13. Disposal Considerations
Waste Disposal Methods: Dispose of material in accordance with federal, state, and local chemical waste regulations, use licensed chemical disposal contractor
Container Disposal: Dispose of contaminated packaging as hazardous waste, do not reuse empty containers unless reconditioned
Precautions: Avoid landfill or sewage disposal, do not dump untreated residues to the environment
Waste Code: Not classified specifically; follow local hazardous waste codes
14. Transport Information
UN Number: Not classified as hazardous for transport under ADR/RID/IMDG/IATA
Proper Shipping Name: Not regulated for transport
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Labeling Requirements: None required for normal quantities under non-hazardous shipping
Environmental Hazards: Not regulated as marine pollutant
Special Transport Precautions: Ensure secure packaging to prevent dust release, protect from moisture and heat during shipment
15. Regulatory Information
U.S. TSCA Inventory: Listed
EU REACH Status: Registered or exempted
Canada DSL/NDSL: Listed
SARA Title III: Not subject to Section 313 reporting
California Prop 65: Not listed as a chemical known to cause cancer or reproductive toxicity
OSHA HazCom Classification: Irritant
Other Local or National Regulations: Subject to standard chemical storage, transport, and disposal requirements
Restriction Information: Check latest local, national, and regional policies for compliance updates
