Dimethyl Sulfone (MSM): Story, Substance, and Significance
Historical Development
A look back at the road leading to widespread MSM use tells a story of curiosity, scientific rigor, and shifting public perceptions. Chemists, scouring the byproducts of lignin processing in the paper industry, stumbled upon MSM nearly a century ago. Their first motivations focused on isolating useful sulfur compounds, hoping one might smooth the path for advancements in agriculture or materials. The story changed in the postwar years, as emphasis shifted from industrial utility to human application. MSM's presence in nature, especially in small quantities in fruit, vegetables, and even rainwater, got more attention. Dermatologists and researchers, noticing its relationship to another sulfur compound—DMSO—took a keener interest. Eventually, nutritionists wondered about its promise for joint health, driving further trials and adjustments in how it was produced and used. Over many decades, MSM's image moved from quirky chemical byproduct to a legitimate research subject, trusted for purity and consistency thanks to ongoing refining of methods and broader regulatory scrutiny.
Product Overview
MSM holds a simple chemical structure that makes it versatile: two methyl groups bonded to a sulfonyl group. It tends to appear as a white, odorless, and slightly bitter powder. Companies package it in bulk for supplement manufacturers or blend it directly into capsules and topical creams. MSM's use spans dietary supplements, veterinary applications, sports nutrition, and increasingly, skin care. Its appeal connects largely to its status as an organosulfur compound naturally found in foods, and as a source of bioavailable sulfur, which plays a role in connective tissues. The supplement industry has fueled a rise in GMP-compliant production, as companies know that purity, consistency, and validated sourcing matter to both consumers and regulators.
Physical & Chemical Properties
Anyone handling pure MSM notices its crystalline form: a fine, stable white powder that dissolves easily in warm water and alcohol. Its melting point sits at about 109°C, and it stays fairly stable at room temperature in dry conditions. The clean, almost odorless nature means MSM can work its way into many formulations without causing sensory issues. Chemically, its formula is C2H6O2S, making it a small and manageable molecule. Stability has big practical implications; MSM withstands modest heating and mixing, so it's suitable for tableting, beverages, or topical delivery. The lack of noticeable reactivity with ordinary supplement ingredients gives formulators freedom. Its solubility in water makes MSM suitable for drinks or topical gels, and because it doesn't clump easily, manufacturers don't battle as many flow challenges in automated filling lines.
Technical Specifications & Labeling
Manufacturers subject MSM to a battery of lab tests, confirming both its physical properties and its chemical purity. Certificates of Analysis typically feature a purity level greater than 99.8%. Residual solvents, heavy metals, and pathogens all get tested for, because supplement brands know that batch-to-batch reliability supports consumer trust and meets regulatory demands. Accurate labeling practices matter as customers want to see clear, upfront information about source, processing, and suggested dosing. Labels will often state “OptiMSM” or “USP Grade,” signaling extra certification and meeting recognized standards. Packaging always needs tamper-evidence and traceability—two requirements that not only protect consumers but also make batch recalls straightforward. Transparency, fostered over years of hard lessons in the supplement business, became the new gold standard.
Preparation Method
Industrial MSM production usually starts with DMSO—dimethyl sulfoxide—sourced from wood pulp or other organic matter, most often through a process involving oxidation. The careful drip of hydrogen peroxide into DMSO, under controlled conditions, transforms it into MSM. Every production step invites rigorous filtration and recrystallization. Impurities get eliminated using activated carbon treatment and repeated washing. Manufacturers often invest heavily in closed processing equipment, minimizing contamination and loss. These steps, though costly, matter to every stakeholder—from ingredient buyers to end users interested in what’s inside their daily dose of MSM. Consistent lot records, as well as cleanroom processing environments, lower contamination risk and ease regulatory audits.
Chemical Reactions & Modifications
MSM, chemically speaking, resists dramatic change under ordinary conditions. It doesn’t break down easily and doesn’t react with most food ingredients. Exposed to strong acids or bases at high temperatures, MSM can decompose, but ordinary supplement and cosmetic formulation doesn’t encounter such extremes. Research has looked into converting MSM back into DMSO or other sulfur-containing products, but the mainstream tech focuses squarely on stability. MSM’s lack of reactivity translates into safety for users, with minimal risk of forming harmful byproducts in everyday handling. Modified versions—specialty derivatives—pop up in niche research circles, but the vast majority of products rely on pure MSM, exploiting its inherent neutral character.
Synonyms & Product Names
Across the chemical supply world, MSM wears a host of names. Besides methylsulfonylmethane—the full IUPAC name—labels might read dimethyl sulfone, DMSO2, or methyl sulfone. The supplement market’s branded varieties, including “OptiMSM” or “PurforMSM,” often point to proprietary purification or licensing agreements. Still, the backbone remains the simple, well-understood structure, making it easy for both scientists and laypeople to track which material they’re discussing. Despite the crowded supplement market, few compound names inspire such clarity—what’s on the label almost always matches what’s in the jar, testament to robust supply chain oversight and established identity testing.
Safety & Operational Standards
Every MSM manufacturer learns quickly that modern quality assurance starts with scrupulous adherence to international standards. Bulk suppliers push for ISO 9001 and cGMP compliance across whole facilities. Auditing routines, environmental controls, and chain-of-custody tracking help to prevent contamination events that once plagued the supplement field. Workers in MSM factories contend with an essentially non-toxic powder, though heavy dust exposures still prompt the use of particulate masks and routine air filtration. Proper warehousing—safeguarding against dampness and pests—protects product integrity over extended storage. MSDS sheets confirm a low acute toxicity profile. As a regular supplement user myself, I value brands that post clear lab reports, sourcing records, and traceability tools. Endorsements from regulatory agencies—the US FDA for GRAS (Generally Recognized As Safe) status, or the EU’s food safety authorities—help clear confusion for medical professionals and the public alike, anchoring MSM’s place in the legitimate health supplement toolbox.
Application Area
MSM branched out from its earliest supplement applications into a host of uses. Human studies link MSM intake to improvements in mild joint discomfort, commonly reported by regular athletes and those with mild osteoarthritis. I’ve seen anecdotal evidence—friends and marathoners passing the word about fewer post-run aches when using MSM capsules or powders. The veterinary world also leans on MSM, folding it into joint supplement blends for dogs, cats, and horses. MSM appears in skin care, touted for soothing redness or supporting wound healing. It grabs a recurring role in shampoos and conditioners for its claimed scalp-support qualities. Though social media sometimes overplays its cosmetic miracles, enough studies and customer feedback nudge MSM deeper into sports recovery and beauty markets. Not everyone experiences dramatic results, but interest in MSM blends well with consumers’ broader search for non-medicinal options for daily discomforts.
Research & Development
Universities and corporate R&D teams keep probing MSM’s mechanisms, reassessing both its strengths and limitations. Researchers from North America, Europe, and Japan regularly publish new trials, often exploring anti-inflammatory properties or MSM’s influence on oxidative stress in cells. Even skeptics admit that MSM attracts more credible clinical work than most supplement ingredients. Some labs are investigating not just direct supplementation, but potential effects on gut microbiota and immune modulation. Electronic lab notebooks record everything from new delivery forms—chewable tablets, topical sprays—to improved analytical assays for detecting contaminants at the parts-per-billion level. As legitimate peer-reviewed research grows, practitioners can recommend MSM with greater confidence, while companies fine-tune production based on new safety and efficacy profiles.
Toxicity Research
Safety studies have piled up over the years, giving a fairly clear picture. High-dose animal and human trials reach intake levels far beyond ordinary daily supplementation and find few concerns. Reports track rare cases of mild digestive upset; even then, symptoms resolve quickly after discontinuing use. Toxicology research focuses on long-term ingestion, looking for remote risks of organ dysfunction or metabolic disruption. So far, data finds no evidence of MSM accumulating in tissues or driving adverse enzyme changes. Regulatory bodies list it among the safest non-pharmaceutical supplements, provided products aren’t adulterated. Most of the worry doesn’t arise from MSM itself, but potential contaminants or cross-reactions with other ingredients, so the best approach continues to be buy from producers who run lot-by-lot impurity scans and post full lab results. Even with MSM’s good track record, vigilance and batch-specific transparency remain true safety nets.
Future Prospects
Looking at trends in health, wellness, and sustainability, the outlook for MSM feels robust. Consumer focus on “natural,” science-backed compounds seems likely to strengthen its market position. New application areas, such as plant-based sports nutrition or medically supervised intervention for chronic pain, might expand MSM’s influence. Tech-driven supply chain improvements, more sophisticated test methods, and increasing regulatory clarity will keep quality high and price reasonable. Researchers may discover fresh insights—not just symptom management but durable impacts on healthy aging and skin repair. Professional organizations, from dietitians’ groups to veterinary medicine boards, are taking notice. The demand for human and animal comfort, less reliant on costly pharmaceuticals, means MSM will stay in the spotlight, especially if manufacturers and scientists keep sharing clear evidence and honest marketing. Everything comes down to informed choices—whether selecting a capsule for knee support or a topical serum for wellness, clear research and transparent sourcing make all the difference.
Understanding MSM's Roots and Role
From hiking trails to gym locker rooms, people talk about MSM as a go-to supplement for joints and inflammation. Long before MSM powders lined the shelves of health stores, sulfur-rich foods quietly supported people’s joints, skin, and hair. MSM just delivers this sulfur in a simple, concentrated form. The body depends on sulfur to keep connective tissues strong and flexible, which helps explain why MSM has found such a solid place among supplements for joint comfort and mobility.
Joints and Muscles: Everyday Relief
Aching knees and stiff hands affect daily routines for millions. MSM has earned its following through both small clinical trials and personal stories of folks who say it helped them keep up with grandkids or finish the gardening they love. Several studies suggest MSM reduces joint pain and swelling, especially for those with osteoarthritis. In arthritis research, MSM supplements helped ease stiffness and improved movement for participants reported in studies published in Osteoarthritis and Cartilage and the International Journal of Biomedical Science. The effect isn’t magic, but those who stick with it often see gradual, real improvements.
Recovery After Exercise
Anyone who pushes hard in a workout knows how tough muscle soreness can be. Weekend warriors and athletes often take MSM to bounce back faster. Research points toward less muscle damage and quicker repair with MSM — pretty appealing after heavy lifting or a long run. Its supporting evidence includes studies published in the Journal of Sports Medicine and Physical Fitness, which saw less soreness and fatigue among supplement users.
Skin, Hair, and Nail Health
Healthy skin isn’t only about lotions. What you eat and supplement shines through in your appearance. MSM provides sulfur, which the body uses for collagen and keratin, the backbone of skin and hair. People dealing with brittle nails or thinning hair sometimes turn to MSM for this reason. Some studies show MSM supplements can improve skin texture and boost hair growth, though research hasn’t reached the same level as joint studies yet. From personal experience, even small shifts in diet or supplement routines can make a noticeable difference in hair strength. Many dermatologists remain cautiously optimistic, pointing to early clinical trials as a reason to keep studying MSM.
Everyday Inflammation and Allergies
Modern life throws enough challenges at immune systems. MSM’s anti-inflammatory properties stem from its ability to block certain chemical signals linked to swelling and discomfort. A few human trials link MSM to lower inflammation markers. People struggling with seasonal allergies share stories of symptoms easing after regular MSM use, and some clinical evidence, like a study in the journal Evidence-Based Complementary and Alternative Medicine, backs this up for certain cases of allergic rhinitis.
Safety and Smart Supplement Choices
Folks interested in MSM want to know it won’t work against them. Studies flag few side effects at moderate dosages, typically up to three grams daily. Some people notice mild stomach upset, but severe reactions remain rare. Still, MSM isn’t a cure-all. Reputable brands offer independent lab testing. Anyone considering long-term use or taking other medications should talk with a healthcare provider. Understanding personal needs and biology beats chasing trends.
Whole-Body Wellness Approach
While MSM has gathered recognition for joint health and reducing inflammation, its broader effects come from giving the body extra sulfur — a mineral many people overlook. Adding MSM to a balanced approach that includes diet, movement, and self-care offers the best chance for long-term wellness. Supplements rarely replace healthy routines, but they can fill gaps that make a real difference throughout the seasons of life.
What Is MSM and Who’s Taking It?
Methylsulfonylmethane, or MSM, makes its way onto the shelves of health stores for anyone dealing with achy joints and chronic inflammation. This sulfur-containing compound comes up a lot in conversations about natural ways to ease arthritis pain or speed up post-workout recovery. You don’t have to dig far into wellness blogs before seeing stories about MSM powder in morning shakes or capsules lining pillboxes.
Common Side Effects in Real-World Use
Plenty of enthusiastic users forget that “natural” doesn’t always mean “risk-free.” Gastrointestinal discomfort turns up often in conversations, especially if someone jumps right into a hefty dose. Bloating, cramps, diarrhea—these aren’t just possibilities on a warning label, they show up in community support groups and informal polls. Ever tried taking a new supplement on an empty stomach and regretted it the rest of the day? Users report this with MSM, and that lesson usually sticks fast.
Skin reactions come next in the list. Some mention a rash or itchy feeling after starting MSM powder or even topical creams. For the unlucky few, hives can lead to a frantic online search for antihistamines or a quick run to the pharmacy. Allergic reactions remain rare but more dramatic, which is why some doctors recommend testing a small amount before diving in.
How MSM Interacts with Prescription Drugs
Anyone on regular medicine needs to pause before reaching for MSM. Taking blood thinners or anti-inflammatory drugs clouds the picture, because MSM may thin the blood slightly or alter how these drugs work. Blood-thinning drugs like warfarin and aspirin come with warnings about adding in new supplements, and MSM stands in that same category. A few years back, someone I know was surprised to see their blood tests change after trying MSM; that led to a tough conversation with their doctor about full disclosure on supplement use.
MSM for Chronic Conditions: Not a Magic Bullet
Plenty of hope gets pinned on MSM as an easy answer for arthritis, allergies, or rosacea. Common sense says moderation rules the day. Research lags behind all the internet claims. Most studies run short and small, often lasting just a few weeks and involving less than a hundred people. Peer-reviewed data points to MSM being generally safe up to 3 grams daily over three months, but that’s only part of the story. Larger, long-term trials are missing. Jumping to higher doses brings extra risk and doesn’t guarantee more benefit.
Looking for Safe MSM Use
Honest conversations between patients and healthcare providers need to happen more often. Bringing up every capsule or powder—over-the-counter or not—is the only way to avoid problems like drug interactions and allergic surprises. Many folks pick MSM after hearing a good story or seeing a positive review, but evidence-based guidance matters. Clear labeling, batch testing for purity, and third-party certifications all help weed out low-quality products that could introduce contaminants.
Kids, pregnant women, and anyone nursing should skip MSM supplementation entirely. Research lacks here, and cautious medical care wins out over internet anecdotes. The popularity wave should never outweigh genuine safety or solid science, no matter how natural a remedy sounds.
Understanding MSM and Its Uses
MSM, short for methylsulfonylmethane, pops up a lot these days in conversations about joint comfort, everyday aches, and even hair and skin support. This sulfur-containing compound shows up in some fruits, veggies, grains, and even in rainwater. It isn’t a flashy supplement, but people noticing creaky knees or skin changes end up searching for it. What grabs attention is how many folks are drawn to MSM because stories float around about its role in easing stiff joints and speeding up post-workout recovery.
Recommended Dosage In Daily Life
Most bottles on store shelves suggest starting at 1,000 to 3,000 milligrams per day. Research scientists often land in this range too. In studies where people wanted to see fewer aches from running, for example, 3 grams (3,000 milligrams) daily sat right in the sweet spot. People living with more persistent joint pain sometimes use up to 6 grams per day, usually split between morning and afternoon. Pills, powders, or crystals—each gets the job done, so the format mostly comes down to what’s easy to swallow or stir into breakfast. From my own time tracking supplement routines, building up gradually often works best. Folks new to MSM who start with a big scoop sometimes get digestive grumbles or mild headaches, a common signal to start slow and work up.
No Magic Number: Everyone’s a Little Different
Science backs up that sulfur balances out inflammatory signals in the body, leading to less soreness and better comfort. Still, our guts, diets, and day-to-day stress can tweak what dosage feels right. People with sensitive stomachs—like me on rough days—feel better starting below the lowest suggested dose. Others with years of athletic mileage who eat lots of fruits and greens might naturally need less. I’ve heard from friends in their late forties, active and health-conscious, that 2 grams keeps their knees happy on long hikes. Others need the larger dose before feeling any difference at all. Listening to your own body matters more than the number printed on a label.
Fact Checks and Real-World Cautions
Results from a review published in the “Nutrients” journal show MSM’s use at daily doses up to 4,000 milligrams led to few side effects. Most folks handle it fine, but as always, tossing it into a complex pile of medications makes things a bit blurry. People on blood thinners or pregnant women, for example, do better getting a green light from a doctor first. MSM supplements face less federal screening than prescription drugs—finding brands with third-party testing, like NSF or USP-certified, adds a layer of trust. A product costing less than a cup of coffee but making huge claims tends to raise red flags for me.
Common Sense Steps For Safe Use
Listening to research and your own body comes before chasing trends. A slow introduction—maybe just half a gram daily for a week—lets any quirks show up early. MSM is an extra, not a replacement for steady movement, getting enough sleep, or balanced meals. Reading labels, matching usage with honest health goals, and checking with health professionals—those steps offer more than any single supplement bottle. From personal experience chasing joint health, small tweaks, consistency, and patience work far better than doubling up on dosages hoping for overnight changes.
The Real Story Behind MSM and Achy Joints
Most people with joint pain have tried almost everything — painkillers, exercise, ice packs, fancy creams. MSM, or methylsulfonylmethane, keeps popping up online as a possible option for stubborn aches. Weekend warriors, grandparents, and office workers all want an answer: does MSM ease the stiffness of arthritis or overuse? Before throwing another bottle into the cart, it pays to look at the facts and real experiences, not just claims on a label.
What MSM Actually Is
MSM is a sulfur-containing compound found in small amounts in fruits, veggies, grains, and milk. It gets processed into capsules and powders. MSM promises to help build healthy cartilage, reduce inflammation, and possibly strengthen skin, hair, and nails. We all know plenty of supplements make big promises, so trusting research and patient experiences means more than trusting pretty packaging.
Scientific Evidence: What Have Researchers Found?
A handful of clinical trials studied MSM in people with osteoarthritis. For example, a 2006 study in the journal Osteoarthritis and Cartilage showed people taking MSM (about 6 grams daily) reported less pain and better use of their joints than those on placebo after 12 weeks. The improvement was moderate — not life-changing, but hard to ignore. Reviews suggest MSM works best as part of a routine alongside exercise, healthy eating, and regular checkups, not as a magic fix.
Research on rheumatoid arthritis isn’t as strong. Most studies include MSM as part of a mix with other supplements, not on its own. Some people notice less swelling or discomfort, but results vary. The supplement market still pushes MSM as a must-have for stiff knees and sore backs, even with mixed evidence.
What Real People Say
I’ve met plenty of folks at fitness classes and neighborhood barbecues who swear by MSM. Some add powders to their morning smoothies; others take capsules every day. Most agree it takes a few weeks before any improvement shows up. The most common report: less morning stiffness and an easier time getting up after sitting. Some feel no different, so not everyone gets results.
Doctors and pharmacists hear similar stories. Most recommend MSM only after trying time-tested steps like physical therapy and weight management. Reliable health sources — like the Arthritis Foundation — remind people MSM is generally safe for most adults in recommended doses but could cause stomach upset and interact with blood thinners. Overuse can mean headaches or sleep trouble, and anyone on medication should check with a professional first.
Cutting Through the Hype: What Makes a Real Difference?
Fancy pills rarely replace basics like movement, diet, and a good pair of shoes. MSM may bring relief to some, especially those with mild achiness instead of advanced arthritis. For people searching for a gentler option before moving to prescription painkillers, MSM could fit in. Medical advice and trustworthy sources matter here; too many websites promise pain-free living in weeks, but few back up their words with solid science. Anyone considering MSM should weigh the cost, possible side effects, and their doctor’s guidance.
Living with joint pain calls for patience and open-mindedness. MSM might be worth a try for some, but it’s no silver bullet. Eat well, move gently, and ask questions. Solid advice usually beats a miracle capsule.
MSM in Daily Life
Methylsulfonylmethane, known as MSM, comes up a lot in conversations about joint health. People use it for everything from mild arthritis aches to hoping their hair grows thicker. The shelves in vitamin stores don’t hide MSM; it’s everywhere, promising relief and flexibility. Some athletes I’ve spoken with swear by it, popping gelatin capsules right after weight training. This interest makes one question how safe it is to use MSM with the mix of supplements or medications so many keep on hand these days.
What Science Says
Backed by decades of basic research, MSM is an organic sulfur compound found in plants, animals, and humans. It's supplied through diet in small amounts—fruits, veggies, grains, cows’ milk all carry some. MSM’s major claim is supporting inflammation control and collagen health. Researchers at the Cleveland Clinic note that evidence for its effectiveness in joint pain relief is moderate, not miraculous. That’s important: MSM won’t quietly fix chronic pain, and anyone who gets off prescription medication without a doctor’s advice risks more harm than good.
Combining MSM with Other Supplements
Plenty of people use MSM with glucosamine or chondroitin, hoping for extra comfort. Studies often combine the three, and current reviews out of Mayo Clinic show low risk if someone is healthy. MSM doesn’t have a track record of clashing with popular vitamins like D, calcium, or fish oil. In personal experience—years sifting through supplement choices—MSM rarely gets flagged on cross-interaction charts alongside common nutrients. The chance of it making a multivitamin less effective is slim.
Herbal supplements paint a trickier picture. Turmeric, ginkgo, ginseng—these have their own quirks and blood-thinning tendencies. Without human trials pairing up these herbs directly with MSM, no one can promise total safety for every mix. The risk gets bigger for anyone using handfuls of herbal blends along with MSM.
MSM and Prescription Medications
The story shifts for those on prescription drugs. MSM has a reputation for playing nice. Allergic reactions stay rare even in medical trials. Drugs for high blood pressure, cholesterol, or mood usually don’t tangle with MSM, based on limited studies and case reports. The U.S. National Institutes of Health points out that no major interactions have been proven so far, but gaps in research remain.
Blood thinners set off the most alarms. MSM may boost the effect of warfarin or aspirin, pushing bleeding risk higher. Older adults or anyone post-surgery should approach with caution. If you rely on prescription medication for a serious condition, any new supplement deserves a chat with a healthcare professional. Pharmacists stay up to date on more supplement-drug combinations than busy doctors do—never underestimate their advice.
Safe Habits and Common Sense
Labels make wild promises, but nothing tops honest communication with doctors. In my own circle, most people take MSM without issue, but they keep it simple: no stacking with complicated herbal mixes, tracking symptoms, and seeking medical advice before adding anything to their regular prescription plan. Simple blood work can spot problems early, giving peace of mind. Some clinics even maintain medication logs for patients who take multiple supplements.
The modern wellness routine often includes MSM. Evidence supports its relative safety when used alone or with most supplements in healthy people. Risks jump once prescription drugs, especially blood thinners, enter the mix. Real safety comes from informed choices, honesty with doctors, and treating supplements with the same respect shown to medication.
| Names | |
| Preferred IUPAC name | methylsulfonylmethane |
| Other names |
Methylsulfonylmethane
Sulfonylbismethane DMSO2 Methyl sulfone |
| Pronunciation | /daɪˈmɛθ.ɪl ˈsʌl.foʊn/ |
| Identifiers | |
| CAS Number | 67-71-0 |
| 3D model (JSmol) | `3D model (JSmol)` string for **Dimethyl Sulfone (MSM)**: ``` CS(=O)(=O)C ``` |
| Beilstein Reference | 1464831 |
| ChEBI | CHEBI:27595 |
| ChEMBL | CHEMBL1232 |
| ChemSpider | 6812 |
| DrugBank | DB00741 |
| ECHA InfoCard | ECHA InfoCard: 100.007.104 |
| EC Number | '67-71-0' |
| Gmelin Reference | 78620 |
| KEGG | C02336 |
| MeSH | D10.570.944.500.600.250 |
| PubChem CID | 7518 |
| RTECS number | PV6210000 |
| UNII | 4O8T4QSHVO |
| UN number | UN3077 |
| CompTox Dashboard (EPA) | DTXSID1022579 |
| Properties | |
| Chemical formula | C2H6O2S |
| Molar mass | 94.13 g/mol |
| Appearance | White crystalline powder |
| Odor | Odorless |
| Density | 1.31 g/cm³ |
| Solubility in water | Soluble |
| log P | -1.1 |
| Vapor pressure | 0.67 hPa (at 25 °C) |
| Acidity (pKa) | ~31 |
| Basicity (pKb) | > 35 |
| Magnetic susceptibility (χ) | -9.6·10⁻⁶ cm³/mol |
| Refractive index (nD) | 1.402 |
| Viscosity | 30-50 cP (25°C) |
| Dipole moment | 3.61 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | 86.3 J·mol⁻¹·K⁻¹ |
| Std enthalpy of formation (ΔfH⦵298) | -564.6 kJ/mol |
| Std enthalpy of combustion (ΔcH⦵298) | -1205.8 kJ/mol |
| Pharmacology | |
| ATC code | A16AX30 |
| Hazards | |
| GHS labelling | GHS07, Warning, H319 |
| Pictograms | GHS07 |
| Signal word | Warning |
| Hazard statements | No hazard statements. |
| Precautionary statements | P261, P264, P270, P272, P280, P301+P312, P330, P501 |
| NFPA 704 (fire diamond) | 1-0-0 |
| Flash point | 130°C (closed cup) |
| Autoignition temperature | 440 °C |
| Explosive limits | Non-explosive |
| Lethal dose or concentration | LD50 Oral Rat 17,000 mg/kg |
| LD50 (median dose) | Oral rat LD50: 17,000 mg/kg |
| NIOSH | RN: 67-71-0 |
| PEL (Permissible) | Not established |
| REL (Recommended) | 10 mg/kg bw |
| Related compounds | |
| Related compounds |
Methanesulfonic acid
Methylsulfonylmethane Dimethyl sulfoxide (DMSO) Methanesulfinic acid Thiomethane (methyl mercaptan) |
