Material Safety Data Sheet (MSDS) for Dipropyl Disulfide

1. Identification

Product Name: Dipropyl Disulfide
Chemical Formula: C6H14S2
Synonyms: 1,1'-Dipropyl Disulfide, Dipropyl Disulphide
CAS Number: 629-19-6
Recommended Use: Laboratory chemicals, research, flavor and fragrance industries
Supplier Information: Emergency phone numbers, address, emergency contact, product support lines, and website addresses

2. Hazard Identification

Classification: Flammable liquid, Acute toxicity (oral, inhalation, dermal), Eye irritation, Skin irritation, Aquatic hazard
Signal Word: Warning
Hazard Statements: May cause skin and eye irritation, harmful if swallowed or inhaled, toxic to aquatic organisms
Pictograms: Exclamation mark, Environmental hazard
Precautionary Statements: Avoid breathing vapors, use protective equipment, wash thoroughly after handling, prevent release into environment
Physical Hazards: Can ignite under standard conditions, vapor can form explosive mixtures

3. Composition / Information on Ingredients

Chemical: Dipropyl Disulfide
CAS Number: 629-19-6
Concentration: More than 98% by weight
Impurities: May contain trace sulfur-containing compounds, which may alter odor or toxicity

4. First Aid Measures

Inhalation: Move exposed person to fresh air immediately, support breathing, seek medical attention if symptoms develop
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for several minutes, seek medical attention for irritation or burns
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, get medical advice as soon as persistent symptoms appear
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical attention due to potential for systemic toxicity

5. Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray
Unsuitable Media: Direct water jet may spread fire
Fire Hazards: Vapors may form explosive mixtures with air, combustion releases toxic and irritating fumes such as sulfur oxides
Protective Equipment: Firefighters should wear full protective gear and self-contained breathing apparatus
Special Procedures: Cool exposed containers with water spray, evacuate area, prevent runoff from entering waterways or drains

6. Accidental Release Measures

Personal Precautions: Evacuate non-essential personnel, ventilate enclosed areas, avoid breathing vapors, use personal protective equipment including gloves, goggles, and respirator
Environmental Precautions: Prevent further leakage or spillage if safe, do not let product enter drains, soil, or water sources due to toxicity to aquatic life
Containment and Cleanup: Soak up with inert material such as sand or vermiculite, collect spillage in container for disposal, wash spill area with water and detergent after cleanup

7. Handling and Storage

Handling: Handle in well-ventilated areas, wear recommended protective equipment, avoid skin and eye contact, do not inhale vapors or mist, wash hands thoroughly after use
Storage: Store in tightly closed original container away from heat and open flames, maintain storage temperature between 2 – 8 °C, keep away from strong oxidizers and acids, store in a dry, cool, and well-ventilated place
Incompatible Materials: Avoid contact with copper alloys and strong oxidizers which may cause dangerous reactions

8. Exposure Controls and Personal Protection

Exposure Limits: No established OSHA or ACGIH exposure limits for dipropyl disulfide, but best practice controls strongly recommended based on chemical group
Engineering Controls: Employ local exhaust ventilation and general room ventilation to reduce exposure, use fume hood when possible
Personal Protective Equipment (PPE): Use chemical-resistant gloves (nitrile preferred), splash-proof goggles, lab coat, and in case of inadequate ventilation, a certified respirator
Hygiene Measures: Remove contaminated clothing immediately, wash hands and face after handling, do not eat, drink or smoke around chemical
Environmental Controls: Prevent release into drain, restrict access for untrained personnel

9. Physical and Chemical Properties

Appearance: Colorless to pale yellow liquid
Odor: Strong, garlic-like odor, typical of sulfur compounds
Odor Threshold: Detectable at low concentrations
pH: Not applicable (non-aqueous)
Melting Point: -55 °C
Boiling Point: 186 °C
Flash Point: 59 °C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid
Vapor Pressure: 0.3 mmHg at 25 °C
Vapor Density: Greater than air
Specific Gravity: 0.95 at 20 °C
Solubility: Immiscible with water, soluble in organic solvents such as ethanol and ether
Partition Coefficient (Log Kow): Estimated at about 3.3
Viscosity: Not available
Decomposition Temperature: Not determined

10. Stability and Reactivity

Chemical Stability: Stable under recommended conditions, may darken or deteriorate upon prolonged exposure to air and light
Reactivity: Reacts with strong oxidizing agents, nitric acid, and bases
Hazardous Decomposition Products: Sulfur oxides (SOx), carbon oxides may form during combustion or decomposition
Conditions to Avoid: Excess heat, open flames, exposure to air, sources of static discharge
Polymerization: No hazardous polymerization expected

11. Toxicological Information

Acute Toxicity: Harmful if swallowed, inhaled, or absorbed through skin; LD50 (oral, rat): ~151 mg/kg, LD50 (dermal, rabbit): not well documented, can cause headaches, dizziness and nausea upon overexposure
Skin Corrosion/Irritation: May cause redness, dryness, burning sensation
Eye Damage/Irritation: Can cause irritation, tearing, redness
Sensitization: No strong evidence for skin sensitization; prolonged or repeated exposure could trigger allergic reaction in sensitive individuals
Chronic Effects: No long-term data available, but repeated workplace exposure can produce liver, kidney and nervous system effects as seen with similar organic sulfur compounds
Carcinogenicity, Mutagenicity: No evidence of carcinogenicity or mutagenicity in short term studies; not listed by IARC, NTP or OSHA
Reproductive Effects: Not established

12. Ecological Information

Ecotoxicity: Highly toxic to aquatic organisms, including fish and invertebrates; prolonged exposure harms aquatic life even at low concentrations
Persistence and Degradability: Substance is not readily biodegradable in standard tests, may persist in water or soil
Bioaccumulative Potential: Significant risk of bioaccumulation in aquatic environments, log Kow suggests moderate potential
Mobility in Soil: Expected to have moderate mobility, but may adsorb to organic matter
Other Adverse Effects: Contributes to unpleasant odor in released environments, forms toxic breakdown products such as sulfur oxides

13. Disposal Considerations

Disposal Methods: Send waste material and contaminated packaging to licensed hazardous chemical disposal facility, do not attempt to treat on-site; incineration is preferred under controlled conditions
Precautions: Ensure waste is disposed in accordance with local, regional, national, and international legislation, do not discharge into drains, waterways or soil
Container Handling: Triple rinse containers before disposal or recycling, puncture and dispose of per hazardous waste regulations

14. Transport Information

UN Number: UN 3334
UN Proper Shipping Name: Aviation regulated liquid, n.o.s. (Dipropyl Disulfide)
Transport Hazard Class: 9 – Miscellaneous Dangerous Substances
Packing Group: III
Environmental Hazards: Marine pollutant, toxic to aquatic life
Transport Labels: Miscellaneous dangerous goods label, marine pollutant mark on bulk packaging
Special Precautions for User: Check country specific and modal requirements; avoid temperature extremes; secure containers well during transport

15. Regulatory Information

Safety, Health and Environmental Regulations/Legislation: Listed or regulated under several local and international chemical control inventories including TSCA (US), DSL (Canada), EINECS (EU), AICS (Australia), and ENCS (Japan)
OSHA Hazards: Classified as hazardous under the OSHA Hazard Communication Standard
SARA Title III: Subject to certain reporting requirements for toxic and hazardous substances
California Proposition 65: Not listed
Other Local Regulations: State and municipal-specific requirements for handling, storage, and disposal may apply; consult regulatory bodies for up-to-date compliance