Methyl Sulfonyl Methane (MSM): Unwrapping the Science, Stories, and Future Potential

Historical Development

MSM has roots stretching back to the days when chemists started paying serious attention to sulfur compounds. Through the twentieth century, research into DMSO (dimethyl sulfoxide) wound up leading to the discovery that MSM, a natural derivative, could offer several of the same sulfur-based benefits without the same pungent aroma or regulatory headaches. In the early eighties, Dr. Stanley Jacob and Dr. Robert Herschler at Oregon Health & Science University began popularizing MSM’s potential for joint comfort and anti-inflammatory properties. MSM moved from laboratories and niche clinics into health food shelves, finding its audience with people looking for a sulfur-based supplement that wasn’t as intimidating as DMSO.

Product Overview

Today, MSM shows up as a white, odorless crystalline powder, sold both as a raw ingredient and pre-packed into capsules, tablets, creams, and drinks. This accessibility makes MSM attractive across a range of consumer products. As someone who once struggled to find niche supplements, I’ve appreciated how easy it’s become to find MSM at almost any store with a health section, from physical shops to the farthest corners of online retailers. Its broad presence matches the swelling demand for simple ingredients backed by both traditional wisdom and modern research.

Physical & Chemical Properties

MSM carries the molecular formula (CH3)2SO2, packing two methyl groups around a central sulfonyl. At room temperature, it looks like a pile of fine, snow-white crystals—no harsh chemical smell, no risk of irritating fumes. Its solubility in water is good, making it useful in drinks and topical gels. Melting point holds near 109°C, which matters if processing includes heating steps or powder blending. MSM won’t play loose or degrade in normal home or supplement shelf conditions. Chemists and formulators who work with it know MSM stays stable and reliable, which keeps it at the top of the list for product development.

Technical Specifications & Labeling

Labels typically display MSM with a stated purity—often 99.9%—along with a batch number and reference to independent lab tests. Regulations in North America and Europe expect labels to mention both the active ingredient and any additives. In food and pharma, compliance isn’t optional. Reputable producers use clear certificate of analysis sheets and list origin, batch identity, and dates. For consumers, this info offers some peace of mind that a jar of MSM is what it claims. On a practical level, cGMP guidelines demand traceability for every ingredient, which means each batch of MSM is tracked from production to bottle.

Preparation Method

Most commercial MSM comes from DMSO, which itself is usually manufactured from wood pulp or lignin sources. The process starts with oxidizing DMSO—sometimes chemically, sometimes using hydrogen peroxide—with results filtered, washed, and crystallized into MSM. It’s possible to synthesize MSM in a lab setting, but large-scale, food-grade MSM sticks with processes that balance efficacy, scalability, and cost. Over the years, improvements in purification have made MSM nearly flavorless and almost entirely free from residual contaminants. Anyone who’s ever brewed their own supplement solutions knows that purity makes all the difference, both for shelf life and for consistency across a product line.

Chemical Reactions & Modifications

On its own, MSM isn’t very reactive under basic storage or usage conditions, which makes it appealing to formulators who want stability. In pharmaceuticals or functional beverages, MSM can blend without unwanted interactions. It can react under strong oxidizing or reducing conditions, but standard preparation and blending rarely trigger these reactions. Some chemists explore modifications, grafting functional groups onto the sulfonyl core to tweak absorption or target specific tissues, though most consumer ingredients keep it simple to prevent side effects or unexplored risks. There’s also exploration of MSM analogs, though pure MSM dominates due to the volume of human and animal safety data already on file.

Synonyms & Product Names

MSM goes by several other names in technical papers or product lists, including dimethyl sulfone and methylsulfonylmethane. In some documentation, you’ll see methyl sulfone, though that can also pop up in reference to other molecules. On shelves, MSM reigns as the most direct and recognizable name for consumers looking for sulfur support or joint comfort. The CAS number 67-71-0 offers a unique identifier for research or regulatory work, making it easier to check sourcing and literature.

Safety & Operational Standards

Years of toxicology and clinical data suggest MSM sits in a comfortable safety range for most users, especially at commonly recommended supplement doses. I’ve talked with athletes and friends who value MSM’s record—minimal side effects, good tolerance even in long-term use, low risk of allergic reactions. Safety guidelines for manufacturers follow strict cGMP protocols to prevent contamination, track ingredient batches, and verify purity. OSHA doesn’t list MSM as particularly hazardous, so handling it in production-scale operations means normal dust controls, eye protection, and workplace ventilation—nothing out of the ordinary compared to similar fine powders.

Application Area

MSM’s strengths play out across several areas—dietary supplements, topical creams, veterinary products, and even as a mild anti-caking agent in feed and food. Fitness enthusiasts, older adults with mobility concerns, and animals with joint issues all represent core users. MSM finds its way into sports recovery formulas, shampoos, bath soaks, and skin gels promising to maintain barrier function or help with redness. Recently, food technologists began testing MSM as a fortification ingredient in functional beverages, looking at its ability to dissolve in water and blend without strong flavor. In cosmetics, MSM features as a skin-calming ingredient, with formulators attracted by its stability and low reactivity.

Research & Development

Basic science keeps building a case for MSM’s value. Studies in the eighties and nineties explored MSM’s anti-inflammatory effects and suggested it may quench oxidative stress in tissues. I’ve seen more recent trials aiming to figure out whether MSM can improve exercise recovery, maintain skin moisture, or modulate allergy responses. Laboratory work has tested MSM’s absorption and metabolism to reassure skeptics and supply answers about how it might interact with medications or other supplements. Universities and contract research labs keep experimenting with dosage forms and delivery routes—powder, spray, gel, even microneedle patches—trying to wring more benefits from the same essential molecule.

Toxicity Research

MSM’s track record looks solid compared to many other ingredients sold without prescription. Dose escalation studies on both animals and humans found few acute toxicity issues, and chronic dosing studies revealed little sign of organ stress or mutagenicity. One meta-analysis summed up that MSM rarely sparks allergic responses, and those who see side effects usually report minor stomach upset that resolves with dose adjustment. Scientists still urge caution for those with sulfur allergies, but the consensus lines up for MSM as one of the safest organosulfur options in foods, supplements, and personal care products.

Future Prospects

MSM holds promise as research finds new roles for sulfur biochemistry in health and disease. As chronic pain and joint discomfort shape wider health conversations, expect product developers to slot MSM into new blends, teaming it with herbal extracts, minerals, or probiotics for broader support. On the industrial side, cleaner and greener manufacturing techniques can help slash costs and improve consumer trust. Ongoing work to map out MSM’s metabolic pathways might inspire targeted delivery forms or new uses beyond joint and skin health. My experience watching consumer awareness grow tells me that MSM’s story is far from over. As more evidence emerges, there’s a real opportunity to see MSM graduate from supplement aisles to become a standard part of lifestyle and clinical wellness strategies.



What are the benefits of taking Methyl Sulfonyl Methane (MSM)?

Understanding MSM and Its Appeal

Methyl Sulfonyl Methane, known in most supplement aisles as MSM, pops up in conversations about joint care, sports recovery, and healthy aging. People keep asking about it, usually after hearing stories from a friend or seeing it in a fitness magazine. MSM is an organic sulfur compound naturally found in some fruits, vegetables, grains, and milk. It’s also present in small amounts in the human body. Scientists have been curious about MSM for decades, and the research behind it grows each year.

Relief for Joint Discomfort

Ask anyone who does physical work, runs marathons, or simply enjoys long walks, and aching joints are a familiar companion. MSM gained a reputation as a go-to supplement for joint pain, especially in the context of osteoarthritis. Studies like the double-blind trial published in “Osteoarthritis and Cartilage” found that people with knee osteoarthritis who supplemented with MSM often reported less pain and better movement than those on placebo. MSM seems to work best for long-term, low-level discomfort by tamping down inflammation—a benefit for anyone who wants to keep active as the years go by.

Reducing Muscle Soreness After Exercise

After a tough day at the gym or a big hike, muscles can feel tight and sore. MSM comes up a lot among athletes and fitness enthusiasts looking for quicker recovery. Research in the “Journal of Sports Medicine and Physical Fitness” showed that MSM supplementation reduced muscle soreness and even markers of muscle damage when paired with exercise. It won’t replace stretching or good nutrition, but MSM looks promising as a small boost for those who push their limits.

Support for Skin and Hair

There’s more to MSM than just caring for what creaks and cracks. Sulfur is a key building block in keratin and collagen, the substances that support hair, skin, and nails. Dermatology studies have highlighted modest improvements in skin elasticity, hydration, and even wound healing when using MSM, either topically or as an oral supplement. People with rosacea or sensitive skin mention it in beauty blogs and forums, though this remains less studied compared to joint health.

Low Risk, But Not For Everyone

Most people tolerate MSM well. Common side effects remain rare and mild, such as stomach upset or headaches. Large-scale safety reviews back this up, so for most adults in good health, there’s little to worry about. That said, anyone who’s pregnant, breastfeeding, on blood thinners, or has ongoing liver or kidney problems should talk to a healthcare provider before picking a supplement off the shelf.

Building on Evidence and Good Habits

Keeping active, eating a balanced diet, and prioritizing rest always matter more than any one supplement. MSM won’t turn back the clock on joint damage or make aches vanish overnight, and full benefit likely comes from combining it with other good habits. The research so far paints a picture of MSM as a supportive tool, not a miracle cure. Picking quality supplements from reputable brands adds another layer of confidence, and consulting qualified health professionals brings peace of mind.

Solutions and Staying Informed

As interest in MSM keeps growing, transparency becomes essential. Seek out products tested for purity. Dig through published studies and real user experiences. In an age of endless wellness options, the best results come from informed decisions, trusted sources, and listening to your own body’s feedback.

Are there any side effects of using MSM supplements?

What Is MSM?

MSM, or methylsulfonylmethane, gets tossed around a lot in the world of joint health and sports nutrition. The supplement racks are full of bottles advertising stronger hair, better skin, relief for aching knees. MSM is a sulfur-containing compound that pops up naturally in fruits, vegetables, grains, and milk. Companies market MSM pills, powders, and creams to folks looking to manage pain or inflammation, or just hoping to shoehorn a bit more 'wellness' into their daily grind.

Real Stories Behind MSM Use

Plenty of people chase MSM hoping it’ll dial down arthritis symptoms. As someone who's watched family members struggle with stiff mornings and hobbled walks, I get the draw of something—anything—that might help. MSM’s reputation for taking the edge off muscle soreness also attracts runners and gym-goers working through tough training cycles.

Supplements make bold promises, but people often forget that anything you take into your system can bring unwanted effects. Even the most natural ingredients may still cause some bumps in the road.

Common Side Effects

Most folks start MSM hoping for benefits and don’t run into too much trouble. Still, complaints do pop up. Stomach issues hit the top of the list. Heartburn, nausea, and diarrhea sometimes show up after a dose. Headaches and trouble sleeping aren’t unheard of. Some people notice skin rashes. For anyone with a sensitive stomach, this can be a dealbreaker; for others, the mild irritation passes after a week or so.

One study in the Journal of Clinical Rheumatology watched adults with osteoarthritis take 1,200mg MSM every day for 12 weeks. Mild side effects showed up in a handful—stomach upset being most frequent, but no major red flags emerged. Reports from people using MSM for skin or hair also mention that these side effects pop up more often in higher doses or when taken on an empty stomach.

Rare But Serious Risks

The U.S. Food and Drug Administration lists MSM as “generally recognized as safe,” but that doesn’t mean everybody gets a free pass. Allergic reactions, although rare, can happen. Swelling, redness, or hives deserve prompt attention. People on blood thinners or medications for diabetes need to keep an eye out—MSM might interact and change the effectiveness of those drugs.

Doctors sometimes see patients mixing MSM with other supplements, thinking more is better, without realizing the chemistry gets complicated quickly. That’s where trouble tends to brew: stacking products with similar effects can lead to unexpected reactions.

Smart Ways to Use MSM

Staying safe starts with listening to your body and double-checking with your healthcare provider. People who jump right into heavy doses tend to struggle more with side effects. Experts often suggest starting low and moving up slowly, watching for problems along the way. If you already take prescription medications, ask a doctor or pharmacist about possible interactions.

Food sources of MSM rarely cause problems in typical diets, but supplement powders and capsules give much higher doses than what you’d get from eating salads or vegetables. This gap in concentration deserves respect. More is not always better.

Moving Forward with Caution

MSM holds real promise for easing joint pain, but it’s not a magic bullet. Anyone thinking about adding MSM to their daily plan should weigh the benefits against the potential for stomach discomfort or drug interactions. Talking things through with a trusted healthcare professional trumps guesswork or internet hype every time. Supplements are popular, but a little caution goes a long way in keeping health plans on track.

How much MSM should I take daily?

MSM or methylsulfonylmethane has become a regular find on supplement shelves. People from athletes to folks with joint pain keep asking: How much do I actually take? With advice ranging from a sprinkle to spoonfuls, it’s easy to get lost.

What MSM Really Does

MSM is a sulfur-based compound. It turns up naturally in some fruits, veggies, and even in small amounts in animal tissue. Most MSM supplements come from chemical synthesis, not natural extraction, but the stuff in capsules lines up with what's found in food. The main draw lies in sulfur’s role. Sulfur helps build healthy bones, joints, skin, and even hair. Many reach for MSM to tackle joint aches, reduce inflammation, or boost recovery after tough workouts.

Understanding the Science Behind Dosing

Research on MSM sits at an awkward crossroads — studies point to potential, but the science isn’t bulletproof. Will MSM wipe away pain? Maybe, maybe not. Published trials often use dosages anywhere from 1,200 mg to 6,000 mg per day divided into two or three doses. Most brands offer capsules at 500 to 1,000 mg each, meaning a typical daily dose involves more than one pill. Joint pain studies, in particular, land around 3,000 mg a day.

No large-scale study pins down a magic number. What matters is starting low and watching how your body responds. Gastrointestinal side effects like bloating or loose stools can crop up if you jump in headfirst or overdo it. I’ve played with MSM over the years for knee soreness. Starting with 1,000 mg in the morning, I waited a week and bumped up by another 1,000 mg. If I felt off, I cut back. Not groundbreaking, but finding your comfort zone often works better than following one-size-fits-all directions.

Safety and Quality Check

Anything labeled as a supplement in the United States skips the strict quality checks carried out for medication. Not every MSM bottle delivers what’s on the label. Shop from brands with third-party testing or certifications. The FDA lists MSM as “generally recognized as safe” up to three grams a day, with some clinical studies running higher. Stomach upset marks the most common complaint in studies; outside of rare cases of allergic reaction, serious side effects show up rarely.

Who Should Be Cautious?

Children, pregnant women, and breastfeeding mothers all fall in the group that needs expert advice before using MSM. Anyone with a serious medical condition or those already juggling several medications should check with a healthcare provider. MSM interacts with a few drugs, like blood thinners. Paying attention to signals from your body makes a difference. No supplement works the same for everyone.

Common-Sense Steps for Starting MSM

Begin with 1,000 to 2,000 mg daily in divided doses. See how it feels for a week. Tweak the amount if needed, but push beyond 3,000 mg only if your doctor gives the green light. Tracking symptoms in a notebook or smartphone helps spot subtle changes in pain, stiffness, or sleep for anyone beginning a new supplement.

Supplements promise plenty, but health builds on basics: eating well, staying active, and finding therapies that fit your own life. MSM deserves its place in the toolbox for some, but it's not a cure-all. Talking it through with a healthcare provider remains the smart move before any new routine.

Is MSM safe to take with other medications or supplements?

Looking at MSM: Why Do People Take It?

MSM, or methylsulfonylmethane, shows up on plenty of supplement shelves these days. Folks try it out for joint pain, inflammation, or sometimes just for an extra boost on tough days. You can spot it in powder or capsule form, and plenty of people swear it helps their bodies feel a bit less creaky. If you have knee pain that flares up after a long walk, you might have given MSM a shot in hopes it’ll ease your steps.

Stories from the Medicine Cabinet

Mixing MSM with other medications and supplements stands out as a real question in my mind. Almost everyone knows someone on a cocktail of pills—blood pressure meds, antidepressants, vitamins, even fish oil or turmeric. A lot of us tend to think of “natural” substances as harmless, but everything that goes in your body can have an impact. Real-life stories prove the point. My own aunt blended MSM into her daily arthritis routine, which also included blood thinners. She felt more limber, but after a week, she started to bruise unusually easily. Turns out, MSM possibly made her blood thinner work a bit too well, so her doctor had her back off.

What We Know from the Science

Reliable information matters, especially when thinking about health. Big research efforts—like those reviewed in journals such as the Journal of Clinical Pharmacology—show few serious problems for healthy adults using MSM by itself. No magic, no horror stories, just solid facts. But studies sometimes miss the strange things that happen when pills mix together in real people. MSM gets broken down by your liver and kidneys, just like other medications do. The chance for unusual reactions grows when you stack MSM with prescription drugs or other herbal supplements, especially blood thinners like warfarin, diabetes drugs, or even simple aspirin. Some folks notice changes in how they feel, while others don’t feel a thing. According to the National Institutes of Health, research on MSM interactions still has a long way to go.

The Risks Worth Thinking About

Here’s where caution matters. People with serious health conditions—especially those on heart medicines or immune suppressants—walk a tighter rope than others. No two bodies work the same way. Sometimes, doctors catch new problems late, after something seems off. Herbal and “natural” supplements can mess with lab results or raise side effect risks. This shows up in real-world reports more than the lab studies say. Those stories, from regular folks to doctors in clinics, help fill in the blanks.

Staying Safe: Steps You Can Take

Nobody wants a supplement to turn a good day bad. Keeping your doctor in the loop just makes sense, especially if you’re considering adding MSM while you already take medications for blood pressure, diabetes, mood, or pain. Track how you feel, even small changes like lightheadedness or stomach problems. If you have a complicated health history, ask your pharmacist too—they’ve spotted interactions before the rest of us noticed a thing. Having a single list of everything you take, pills and powders, helps the whole care team spot problems early.

Looking Ahead

Everyone wants to feel better. Products like MSM attract attention, but combining them with other medicines creates real blind spots. Open talks with health professionals help fill those gaps, so curiosity or hope doesn’t end up causing harm. That’s how we each take ownership of health—step by step, with good advice and real information at our backs.

What is MSM commonly used for in health and wellness?

MSM, Joints, and Why People Swear By It

It doesn’t take long on wellness forums before methylsulfonylmethane—better known as MSM—gets brought up in joint pain discussions. As someone who’s dealt with creaky knees thanks to years on soccer fields, I get why MSM grabs attention. People want relief that doesn’t involve prescription bottles. MSM is an organic sulfur compound found in small amounts in fruits, vegetables, grains, and animals, and you’ll spot it on supplement shelves everywhere.

MSM draws its popularity from claims related to pain support. Folks living with osteoarthritis or just dealing with overuse from workouts look for something that could give them a break. There’s more than just internet chatter behind MSM’s use; published research highlights its impact on reducing joint pain and swelling. For example, a study in Osteoarthritis and Cartilage in 2006 had patients take MSM for three months. Those using MSM reported less pain and better movement than those on a placebo. Another group of athletes found MSM helped curb muscle soreness after intense exercise sessions, which lines up with how some trainers and runners talk about using it during recovery periods.

Getting Behind the Science and Claims

People talk a lot about MSM’s anti-inflammatory effects. This isn’t marketing spin—sulfur plays a central role in repairing and building tissues, especially collagen. Research shows MSM can slow down inflammatory signals that keep joint pain and swelling going. The supplement also seems to lower oxidative stress, which gets talked about with “aging gracefully” and staying limber as you rack up birthdays.

Not all the enthusiasm matches the evidence, though. Some studies show smaller benefits, or improvement that doesn’t last long. It reminds me of conversations in community gyms: one person raves about it, another shrugs it off. Supplements work differently for everyone. MSM gets paired with glucosamine and chondroitin in many products, so teasing out what’s helping can be tricky. Plus, lifestyle choices—moving daily, sleeping enough, not overdoing junk food—always shape results more than a single pill or powder.

MSM Beyond Joints: Skin, Hair, and Allergy Relief

After reading up on MSM for knees, I spotted testimonials about brighter skin and fuller hair. People use it hoping it will improve elasticity thanks to its sulfur content. There’s some preliminary research backing this—not enough to hang major health claims on, but enough for beauty brands to load MSM into creams and shampoos. MSM is also popular with people dealing with allergies. A small study from Oregon Health & Science University hinted at reduced allergy symptoms after using MSM, but larger trials haven’t settled the debate. Every allergy sufferer I know tries a lot of things, so MSM joins a long queue of “possible helps.”

What to Look Out For

MSM tends to be safe for most people, based on research and feedback from supplement users. Upset stomach pops up sometimes, especially with high doses or empty-stomach experiments. Anyone taking blood thinners or managing serious health issues needs to talk with a doctor before starting a new supplement. You can buy MSM in powders, capsules, and blended formulas. Look for brands you trust and check test results for purity, because supplements aren’t screened by the FDA before hitting shelves.

Ideas Worth Considering

Supplements like MSM shouldn’t crowd out attention to basics. Over years of talking with physical therapists and tackling my own pain, I’ve learned that supporting joints means mixing movement, nutrition, and enough rest. MSM gets plenty of word-of-mouth because it fits in a toolkit—for some, it feels like a solid piece. Studying up, asking doctors, and staying honest about what works remain the smartest ways to figure out any supplement’s role in a wellness plan.

Methyl Sulfonyl Methane(MSM)
Names
Preferred IUPAC name methylsulfonylmethane
Other names Dimethyl sulfone
DMSO2
Sulfonylbismethane
Methylsulfonylmethane
Pronunciation /ˈmɛθ.ɪl sʌlˈfɒn.ɪl ˈmɛθ.eɪn/
Preferred IUPAC name methylsulfonylmethane
Other names Dimethyl sulfone
Methylsulfonylmethane
DMSO2
Sulfonylbismethane
Pronunciation /ˈmɛθ.ɪl sʌlˈfɒnɪl ˈmɛθ.eɪn/
Identifiers
CAS Number 67-71-0
3D model (JSmol) `3D model (JSmol)` string for **Methyl Sulfonyl Methane (MSM)**: ``` CS(C)(=O)=O ```
Beilstein Reference 1718735
ChEBI CHEBI:5784
ChEMBL CHEMBL1239
ChemSpider 7287
DrugBank DB13983
ECHA InfoCard 100.028.257
EC Number EC 231-815-0
Gmelin Reference 39712
KEGG C03010
MeSH D020085
PubChem CID 6213
RTECS number OA5504000
UNII F82XA37482
UN number UN3249
CompTox Dashboard (EPA) DTXSID6022210
CAS Number 67-71-0
3D model (JSmol) `CS(=O)(=O)C`
Beilstein Reference 1720536
ChEBI CHEBI:18361
ChEMBL CHEMBL1230500
ChemSpider 5216
DrugBank DB01144
ECHA InfoCard 100.027.954
EC Number EC 231-815-0
Gmelin Reference 8782
KEGG C02385
MeSH D017388
PubChem CID 6213
RTECS number OA5504000
UNII 6C6C2CF5KG
UN number NA3077
CompTox Dashboard (EPA) DTXSID3024676
Properties
Chemical formula C2H6O2S
Molar mass 94.13 g/mol
Appearance White crystalline powder
Odor Odorless
Density 1.34 g/cm³
Solubility in water Soluble in water
log P -1.1
Vapor pressure < 0.01 mmHg (25°C)
Acidity (pKa) 31.1
Basicity (pKb) Basicity (pKb): 15.57
Magnetic susceptibility (χ) -7.6 × 10⁻⁶
Refractive index (nD) 1.422
Viscosity 30 mPa.s (20°C)
Dipole moment 3.94 D
Chemical formula C2H6O2S
Molar mass 94.13 g/mol
Appearance White crystalline powder
Odor Odorless
Density 1.45 g/cm³
Solubility in water Soluble in water
log P -1.1
Vapor pressure <0.01 hPa (20 °C)
Acidity (pKa) 31.1
Magnetic susceptibility (χ) -9.9 × 10⁻⁶ cm³/mol
Refractive index (nD) 1.434
Viscosity 20-40 mPa.s (20°C)
Dipole moment 3.06 D
Thermochemistry
Std molar entropy (S⦵298) 268.6 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -382.6 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -802.5 kJ/mol
Std molar entropy (S⦵298) 90.5 J·mol⁻¹·K⁻¹
Std enthalpy of formation (ΔfH⦵298) -382.53 kJ/mol
Std enthalpy of combustion (ΔcH⦵298) -802.8 kJ/mol
Pharmacology
ATC code A13AX – Other anabolic agents
ATC code A13AX20
Hazards
Main hazards May cause eye, skin, and respiratory tract irritation
GHS labelling GHS07, Exclamation mark
Pictograms GHS07
Signal word No signal word
Hazard statements May cause eye irritation.
Precautionary statements Keep out of reach of children. If pregnant or breastfeeding, consult a health professional before use. Store in a cool, dry place. Do not use if safety seal is broken or missing.
NFPA 704 (fire diamond) 1-0-0
Flash point Flash point: 146°C
Autoignition temperature Autoignition temperature: 224°C (435°F)
Explosive limits Not explosive
Lethal dose or concentration LD50 (oral, rat): > 17,000 mg/kg
LD50 (median dose) Oral LD50 (rat): >17,000 mg/kg
NIOSH PB63600
PEL (Permissible) Not established
REL (Recommended) 1300 mg
Main hazards May cause eye, skin, and respiratory irritation.
GHS labelling GHS07, GHS precautionary statements
Pictograms GHS07, GHS08
Signal word No signal word
Hazard statements No known significant effects or critical hazards.
Precautionary statements Keep container tightly closed. Store in a cool, dry, and well-ventilated place. Avoid contact with eyes, skin, and clothing. Wash thoroughly after handling. Do not ingest. Use personal protective equipment as required.
NFPA 704 (fire diamond) 1-0-0
Flash point 135°C
Lethal dose or concentration LD50 (oral, rat): > 20,000 mg/kg
LD50 (median dose) Oral LD50 (rat): > 17,000 mg/kg
PEL (Permissible) Not established
REL (Recommended) 1300 mg
IDLH (Immediate danger) Not established
Related compounds
Related compounds Dimethyl sulfoxide (DMSO)
Methanesulfonic acid
Sulfur
Methionine
Sulfonamides
Sulfonic acids
Methylsulfinylmethane
Related compounds Dimethyl sulfoxide (DMSO)
Methanesulfonic acid
Sulfur dioxide
Methionine
Dimethyl sulfide