MSDS for Thiodiglycolic Acid

Identification

Product Name: Thiodiglycolic acid
Synonyms: 2,2'-Dithiodiacetic acid,
Chemical Formula: C4H6O4S2
CAS Number: 123-93-3
Recommended Use: Intermediate in chemical synthesis, sometimes used in research labs
Manufacturer/Supplier: Chemical suppliers and manufacturers relevant to laboratory and industrial supply chains
Contact Number: Emergency hotlines provided by suppliers, such as CHEMTREC

Hazard Identification

GHS Classification: Causes serious eye irritation, may cause skin irritation, may be harmful if swallowed
Hazard Pictograms: Exclamation mark (for irritation)
Signal Word: Warning
Hazard Statements: H315—Causes skin irritation; H319—Causes serious eye irritation; H302—Harmful if swallowed
Precautionary Statements: Wear protective gloves/eye protection, avoid inhalation of vapors or mists, wash hands thoroughly after handling
Potential Health Effects: Eye and skin contact cause irritation, ingestion may disturb gastrointestinal tract

Composition / Information on Ingredients

Chemical Identity: Thiodiglycolic acid
CAS Number: 123-93-3
Concentration: 98% or higher (depending on product grade and manufacturer)
Impurities: Minor moisture content and residual byproducts from synthesis
Stabilizers: Typically none, pure acid as supplied

First Aid Measures

Inhalation: Move individual to fresh air, consult physician if respiratory symptoms develop, provide artificial respiration if breathing stops
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with water for several minutes, wash affected area with soap and water, seek medical attention for persistent irritation
Eye Contact: Rinse opened eye gently with plenty of water for several minutes, remove contact lenses if present and easy to do, get medical help for continued pain or vision change
Ingestion: Rinse mouth out with water, do not induce vomiting, never give liquids to unconscious individual, consult physician or poison control center for medical advice
Most Important Symptoms and Effects: Burning sensation, redness, discomfort, possible eye damage
Immediate Medical Attention: Needed for severe exposure or if symptoms persist

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Specific Hazards: Thermal decomposition releases toxic gases including sulfur oxides, carbon monoxide, carbon dioxide
Protective Equipment: Self-contained breathing apparatus and full protective fire-resistant clothing
Firefighting Instructions: Isolate hazard area, use water spray to cool nearby containers, avoid inhalation of fumes
Combustion Products: Sulfur oxides, carbon oxides, possibly other irritants
Explosion Data: Not classified as explosive under normal conditions

Accidental Release Measures

Personal Precautions: Wear appropriate personal protective gear, restrict unnecessary entry, ensure adequate ventilation
Environmental Precautions: Prevent discharge to drains, waterways, or soil to reduce harmful impact on aquatic life
Cleanup Methods: Absorb spill with inert material such as sand or diatomaceous earth, sweep up and place in suitable, labeled waste container, clean contaminated surface thoroughly
Spill Reporting: Notify proper authorities according to local regulations, particularly for large releases

Handling and Storage

Safe Handling Advice: Use with proper ventilation, avoid inhalation and contact with skin, eyes, or clothing, never eat or drink while handling chemicals
Hygiene Practices: Wash thoroughly after handling, remove contaminated clothing before entering eating areas
Storage Conditions: Store in tightly closed containers, keep in a cool, well-ventilated area, protect from light, heat, and incompatible substances like strong oxidants
Storage Temperature: Generally stored at ambient room temperature, away from incompatible substances

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established OSHA or ACGIH exposure limits, but minimize exposure as much as possible
Engineering Controls: Work in chemical fume hood or well-ventilated area
Personal Protection: Chemical-resistant gloves, safety goggles or face shield, lab coat or apron, respiratory protection if ventilation insufficient
Environmental Controls: Keep emissions to air and wastewater to minimum

Physical and Chemical Properties

Physical State: White crystalline solid or powder
Odor: Faint sulfurous or acetic odor
pH: Acidic when dissolved in water
Melting Point: Approximately 93°C (199.4°F)
Boiling Point: Decomposes before boiling
Solubility: Freely soluble in water, slightly soluble in alcohol
Molecular Weight: 182.22 g/mol
Density: Roughly 1.7 g/cm³
Vapor Pressure: Not significant at room temperature
Partition Coefficient (n-octanol/water): Not determined
Flash Point: Not applicable (non-volatile solid)
Autoignition Temperature: No data available
Evaporation Rate: Not applicable
Appearance: Solid, white crystalline material

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Thermal Decomposition: Releases sulfur oxides, carbon oxides above decomposition temperature
Incompatible Materials: Strong oxidizers, strong acids, bases, reducing agents
Hazardous Polymerization: Does not occur
Reactivity: Reacts with bases and oxidizing chemicals, avoid contact with reactive substances
Conditions to Avoid: Excessive heat, light, exposure to incompatible materials

Toxicological Information

Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: LD50 (oral, rat): Approximately 200-2000 mg/kg (values vary in literature)
Skin Irritation: Causes irritation upon prolonged or repeated exposure
Eye Irritation: Causes severe irritation, possible corneal injury
Inhalation: Vapors or mists may cause irritation to respiratory tract
Chronic Toxicity: Long-term exposure has not been fully studied, no known carcinogenicity or reproductive toxicity
Target Organs: Eyes, skin, mucous membranes
Symptoms: Burning, redness, tearing, coughing, abdominal upset if ingested

Ecological Information

Aquatic Toxicity: May be harmful to aquatic organisms in high concentrations
Degradability: Readily biodegradable in the environment, breaks down to carbon dioxide and sulfates
Bioaccumulative Potential: Low potential for bioaccumulation
Mobility in Soil: Relatively mobile, especially in wet conditions
Other Ecological Effects: Avoid uncontrolled environmental release to prevent disruption of local ecosystems

Disposal Considerations

Disposal Methods: Dispose of contents and container in accordance with local, regional, and national regulations, avoid discharge to drain or waterway
Contaminated Packaging: Empty containers retain product residue, triple rinse before disposal, follow hazardous waste guidelines
Special Precautions: Use qualified chemical waste handler, do not attempt disposal by landfill or incineration without permitting

Transport Information

UN Number: Not regulated as dangerous good under most transport regulations
Proper Shipping Name: Thiodiglycolic acid or appropriate chemical name
Transport Hazard Class: Not classified as hazardous
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: Keep container sealed and upright, transport in secure and ventilated manner

Regulatory Information

US Regulations: Not specifically listed under TSCA 12(b), SARA Title III, or CERCLA; general chemical safety laws apply
EU Regulations: Considered hazardous under Regulation (EC) No 1272/2008, subject to CLP/GHS labeling
Canada: DSL/NDSL status varies, ensure compliance with WHMIS requirements
Other Regulations: Check requirements in country of use, always update based on latest published guides from chemical authorities